Reports of Radiotherapy and Oncology

Published by: Kowsar

Extramedullary Plasmacytoma of the Maxillary Sinus with Intra-Orbital Extension: A Case Report of a Rare Condition

Abolfazl Taheri 1 , Hassan Shamsaei 2 and Hadi Sharouny 1 , *
Authors Information
1 Department of Otorhinolaryngology Head and Neck Surgery, Baqiyatallah Hospital, School of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran
2 Department of Pathology, Baqiyatallah Hospital, School of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran
Article information
  • Reports of Radiotherapy and Oncology: 5 (1); e82423
  • Published Online: January 7, 2019
  • Article Type: Case Report
  • Received: July 20, 2018
  • Revised: September 19, 2018
  • Accepted: October 13, 2018
  • DOI: 10.5812/rro.82423

To Cite: Taheri A, Shamsaei H, Sharouny H. Extramedullary Plasmacytoma of the Maxillary Sinus with Intra-Orbital Extension: A Case Report of a Rare Condition, Rep Radiother Oncol. Online ahead of Print ; 5(1):e82423. doi: 10.5812/rro.82423.

Copyright © 2019, Reports of Radiotherapy and Oncology. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Introduction
2. Case Presentation
3. Discussion
  • 1. Attanasio G, Viccaro M, Barbaro M, De Seta E, Filipo R. Extramedullary plasmacytoma of paranasal sinuses. A combined therapeutic strategy. Acta Otorhinolaryngol Ital. 2006;26(2):118-20. discussion 120. [PubMed: 16886855]. [PubMed Central: PMC2639977].
  • 2. Rajkumar SV, Kyle RA, DeLaney TF, Connor RF. Diagnosis and management of solitary extramedullary plasmacytoma. UpToDate. 2017.
  • 3. Wiltshaw E. The natural history of extramedullary plasmacytoma and its relation to solitary myeloma of bone and myelomatosis. Medicine (Baltimore). 1976;55(3):217-38. doi: 10.1097/00005792-197605000-00002. [PubMed: 1272069].
  • 4. Kapadia SB, Desai U, Cheng VS. Extramedullary plasmacytoma of the head and neck. A clinicopathologic study of 20 cases. Medicine (Baltimore). 1982;61(5):317-29. doi: 10.1097/00005792-198209000-00004. [PubMed: 6180279].
  • 5. Meis JM, Butler JJ, Osborne BM, Ordóñez NG. Solitary plasmacytomas of bone and extramedullary plasmacytomas a clinicopathologic and immunohistochemical study. Cancer. 1987;59(8):1475-85.
  • 6. Sulzner SE, Amdur RJ, Weider DJ. Extramedullary plasmacytoma of the head and neck. Am J Otolaryngol. 1998;19(3):203-8. doi: 10.1016/S0196-0709(98)90089-8. [PubMed: 9617934].
  • 7. Cantone E, Di Lullo AM, Marano L, Guadagno E, Mansueto G, Capriglione P, et al. Strategy for the treatment and follow-up of sinonasal solitary extramedullary plasmacytoma: A case series. J Med Case Rep. 2017;11(1):219. doi: 10.1186/s13256-017-1382-4. [PubMed: 28793931]. [PubMed Central: PMC5550939].
  • 8. Ashraf MJ, Azarpira N, Khademi B, Abedi E, Hakimzadeh A, Valibeigi B. Extramedullary plasmacytoma of the nasal cavity report of three cases with review of the literature. Iran Red Crescent Med J. 2013;15(4):363-6. doi: 10.5812/ircmj.2209. [PubMed: 24083014]. [PubMed Central: PMC3785915].
  • 9. Swerdlow SH, Campo E, Pileri SA, Harris NL, Stein H, Siebert R, et al. The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood. 2016;127(20):2375-90. doi: 10.1182/blood-2016-01-643569. [PubMed: 26980727]. [PubMed Central: PMC4874220].
  • 10. Ching AS, Khoo JB, Chong VF. CT and MR imaging of solitary extramedullary plasmacytoma of the nasal tract. AJNR Am J Neuroradiol. 2002;23(10):1632-6. [PubMed: 12427612].
  • 11. Creach KM, Foote RL, Neben-Wittich MA, Kyle RA. Radiotherapy for extramedullary plasmacytoma of the head and neck. Int J Radiat Oncol Biol Phys. 2009;73(3):789-94. doi: 10.1016/j.ijrobp.2008.04.077. [PubMed: 18707826].
  • 12. Tournier-Rangeard L, Lapeyre M, Graff-Caillaud P, Mege A, Dolivet G, Toussaint B, et al. Radiotherapy for solitary extramedullary plasmacytoma in the head-and-neck region: A dose greater than 45 Gy to the target volume improves the local control. Int J Radiat Oncol Biol Phys. 2006;64(4):1013-7. doi: 10.1016/j.ijrobp.2005.09.019. [PubMed: 16343803].
  • 13. Wen G, Wang W, Zhang Y, Niu S, Li Q, Li Y. Management of extramedullary plasmacytoma: Role of radiotherapy and prognostic factor analysis in 55 patients. Chin J Cancer Res. 2017;29(5):438-46. doi: 10.21147/j.issn.1000-9604.2017.05.08. [PubMed: 29142463]. [PubMed Central: PMC5677129].
  • 14. Armstrong WB, Vokes DE, Verma SP. Malignant tumors of the larynx. In: Flint PW, Haughey BH, Lund VJ, Niparko JK, Robbins KT, Thomas JR, editors. Cummings otolaryngology head and neck surgery. 6th ed. Elsevier; 2015. p. 1601-33.
  • 15. Soo G, Chan A, Lam D, Abdullah V, van Hasselt CA. Extramedullary nasal plasmacytoma--an unusual clinical entity. Ear Nose Throat J. 1996;75(3):171-3. [PubMed: 8721023].

Featured Image:

Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments